Supervisions and Teaching

Supervisions

If I have seen further it is by standing on the shoulders of giants

Isaac Newton

On another side, young colleagues are also crucial and valuable « shoulders » for our research projects.
I would like here to thank those who worked or are working with me during my career!

PhD students

  • Aurora De La O Espadas (2023-…): Development of microfluidic instrumented device to study and optimize interactions between nanoparticles and blood’s proteins. Co-supervised with Pr. Thérèse Leblois. University of Burgundy and University of Franche-Comté (France).
  • Dorra Ben Elkadhi (2023 – …): Nanoparticles in the blood: optimization and control of the protein corona. Co-supervised with Dr. Arnaud Ponche. University of Burgundy (France).
  • Célia Marets (2019-2023): Elaboration of inorganic nanoparticles for the study of nanoparticle-protein interactions. Co-supervised with Dr. Lucien Saviot. Thesis defended le 18/10/2023 at University of Burgundy (France).
  • Annette Luce (2016-2020): Innovative bioassays to evaluate the toxicity of nanoparticles. Not officially supervised as her two « real » supervisors (2 only were allowed) were Pr. Marie-Christine Chagnon and Pr. Nadine Millot. Thesis defend the 03/03/2020 at University of Burgundy (France).
  • Usawadee Sakulkhu (2011-2013): Preparation of coated nanoparticles and investigation of their behavior in biological environment. Co-supervised with Pr. Heinrich Hofmann. Thesis defended the 02/05/2013 at EPFL (Switzerland).
Valorisations

Nanoparticles: Drug Inhalation Therapy – Events at Air-Blood Tissue Barrier
A fast and reproducible method to quantify magnetic nanoparticles biodistribution
Syntheses of cross-linked polymeric superparamagnetic beads with tunable properties
Protein Corona Composition of Superparamagnetic Iron Oxide Nanoparticles with Various Physico-Chemical Properties and Coatings
Ex situ evaluation of the composition of protein corona of intravenously injected superparamagnetic nanoparticles in rats
Significance of surface charge and shell material of Super-paramagnetic Iron Oxide Nanoparticles (SPIONs) based core/shell nanoparticles on the composition of the protein corona
Beyond unpredictability: the importance of reproducibility in understanding the protein corona of nanoparticles
In vivo protein corona on nanoparticles: does the control of all material parameters orient the biological behavior?
Identification of the Proteins Determining the Blood Circulation Time of Nanoparticles (more infos)

Master thesis

  • Emma Brunin (2024): Synthesis and functionalization of gold nanoparticles in a continuous way. Engineering school ENSIC from Nancy (France). Student hired by SON SAS.
  • Leya Liu (2023): Stabilization and functionalization of sepiolite nanoparticles. Master 2 and engineering diplomas of material sciences from University of Burgundy (France).
  • Aicha Hamidi (2022): Development of Nanoparticles & understanding and control of their blood interactions. Master of nanosciences from University of Strasbourg (France).
  • Sullivan Guy (2021): Studies and control of the surface chemistry of nanoparticles for better interaction with proteins. Master 2 of molecular chemistry from University of Burgundy (France).
  • Dihia Refsi (2019): Iron oxide nanoparticles for biomedical applications: influence of surface chemistry on their biological behaviors. Master of drug design from University of Caen (France).
  • Amar Alok (2019): Synthesis of gold and silver nanoparticles for studies of stability. Master of physics, photonics and nanotechnology of University of Burgundy (France).
  • Victoire Asila (2018): Iron oxide nanoparticles for medical imaging and therapy: synthesis, functionalization and biocirculation study. Master of chemistry of materials from UPMC Paris (France)
  • Manon Giraud (2015): Investigation of the proteins affinity for negatively charged Silica–coated Superparamagnetic Iron Oxide Nanoparticles. Master of materials from EPFL (Switzerland).
  • Noelie Cayla (2014): Investigation of the protein affinity of negatively charged Silica-coated Superparamagnetic Iron Oxide Nanoparticles. Master of materials from EPFL (Switzerland).
  • Mehdi Ahmadi (2013): Co-encapsulation of superparamagnetic iron oxide and gold nanoparticles by silica coating via microemulsion method. Master of materials from EPFL (Switzerland).
  • Alexis Claveau (2013): Investigation and optimization of the covalent grafting of polymers on SPIONs by cross-linking of silica precursors. Master of materials from EPFL (Switzerland).
  • Katarina Ilic (2012): Understanding the Transport Processes of Nanoparticles in Fluidic Media. Co-funder and revenue director of Voltera.
  • Vanessa Mai Dao (2012): Fluorescent Magnetic Nanoparticles for Biomedical Applications. Master of materials from EPFL (Switzerland).
  • Nicolas Leclaire (2012): Synthesis and characterization of silica-coated superparamagnetic iron oxide nanoparticles for biomedical applications. Master of materials from EPFL (Switzerland). Master of materials from University of Waterloo (Canada).
  • Jérémy Paris (2010): Elaboration of iron oxide nanoparticles for biomedical applications: synthesis and functionalization. Master of nanosciences from University of Burgundy (France). Director of SON SAS.
Valorisations

One step continuous hydrothermal synthesis of very fine stabilized superparamagnetic nanoparticles of magnetite
Syntheses of cross-linked polymeric superparamagnetic beads with tunable properties
Polymer adsorption on iron oxide nanoparticles for one-step amino-functionalized silica encapsulation
Beyond unpredictability: the importance of reproducibility in understanding the protein corona of nanoparticles

Other shorter collaborations

  • Cintia Marques (10/2019 and 06/2023): Syntheses of stabilized iron oxide nanoparticles to study their interactions with proteins. Collaborations with University of Geneva.
  • Nadia von Moos (2011-2015): Acute oxidative stress responses in the microalga Chlamydomonas reinhardtii exposed to metal oxide nanoparticles. Thesis defend the 29/06/2015.
  • Dr. Weerakanya Manneeprakorn (09/2011-11/2011 and 2 visits in Thailand in 2013 and 2014): Technology transfert for a new thematic on biocompatible iron oxide nanoparticles; Exchanges between EPFL and Nanotec in Thailand.
  • Noemi Aguilo Aguayo (03/2011-05/2011): Production and characterisation of carbon-encapsulated iron nanoparticles by arc-discharge plasma. 3 months visit at EPFL in 2011 during here PhD.
Valorisations

Aqueous stabilisation of suspensions of carbon-encapsulated superparamagnetic nanoparticles for biomedical applications
Silica-coated superparamagnetic nanoparticles as contrast agent for magnetic resonance imaging: Synthesis and physiological characterizations
Pro-oxidant effects of nano-TiO2 on Chlamydomonas reinhardtii during short-term exposure
Superparamagnetic nanohybrids with cross-linked polymers providing higher in vitro stability
Characterization of liposome-containing SPIONs conjugated with anti-CD20 developed as a novel theranostic agent for central nervous system lymphoma
Beyond unpredictability: the importance of reproducibility in understanding the protein corona of nanoparticles
Characterization Challenges of Self-Assembled Polymer-SPIONs Nanoparticles: Benefits of Orthogonal Methods
Identification of the Proteins Determining the Blood Circulation Time of Nanoparticles (more infos)


Teaching

Since 2017 (Université of Burgundy)

  • Master level (ESIREM): Supervised practical work on elaboration of nanomaterials
  • Master level (Master CAC): 1 month project on analytical chemistry
  • Master level: Supervisions of 4 months project abroad

2011-2015 (EPFL)

  • Bachelor to PhD level (Institute of Materials): Lectures and practical works on synthesis and characterizations of nanomaterials