Congratulations to Célia Marets for the defense of her thesis entitled: Elaboration of inorganic nanoparticles for the study of nanoparticle-protein interactions.
Her work focused on the development of a library of nanoparticles (gold, iron oxide and silica) with different biocompatible coatings in order to study their interactions with serum and plasma proteins.
She also studied in vivo the protein corona formation on nanoparticles to correlate it to their biocirculation with an important part dedicated on bibliography and statistical processing.
Célia presented her work on Wednesday the 18th of October in front of the following jury:
| Nadine Millot | Professor, University of Bourgogne | President of jury |
| Martine Meireles | Research director CNRS, University of Toulouse | Reviewer |
| Damien Mertz | Researcher CNRS, University of Strasbourg | Reviewer |
| Valérie Forest | Professor, Ecole des Mines St Etienne | Examiner |
| Olivier Jordan | Professor, University of Geneva, Switzerland | Examiner |
| Lionel Maurizi | Researcher CNRS, University of Bourgogne | Co-director |
| Lucien Saviot | Research director CNRS, University of Bourgogne | Co-director |
The jury expressed its congratulations and found that Celia demonstrated a strong scientific rigor.
Célia project was funded by the EUR EIPHI and the ANER project Nanoprot.
Célia published a review on in vivo protein corona that was in the top 5% of the most cited of the Royal Society of Chemistry in 2022.
In vivo protein corona on nanoparticles: does the control of all material parameters orient the biological behavior?; Nimisha Singh, Célia Marets, Julien Boudon, Nadine Milllot, Lucien Saviot and Lionel Maurizi ; Nanoscale Advances ; 2021 ; 3 ; 5 ; 1209-1229. Link
Celia also collaborated with University of Geneva and Stanford Medicine to publish her results on in vivo protein corona.
Identification of the Proteins Determining the Blood Circulation Time of Nanoparticles ; Cintia Marques, Mohammad Javad Hajipour, Célia Marets, Alexandra Oudot, Reihaneh Safavi-Sohi, Mélanie Guillemin, Gerrit Borchard, Olivier Jordan, Lucien Saviot and Lionel Maurizi ; ACS Nano; 2023; 17; 13; 12458–12470. Link